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KMID : 1144320120440010011
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감염과 화학요법
2012 Volume.44 No. 1 p.11 ~ p.16
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Comparison of the Incidence and Clinical Characteristics of Gram-positive and Gram-negative Surgical Site Infections after Gastric Surgery
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Kim Hye-Won
Kim Chang-Oh
Jeong Su-Jin
Han Sang-Hoon
Choi Jun-Yong
Kim Min-Ja
Choi Young-Hwa
Im Seung-Guan
Yeom Joon-Sup
Park Yoon-Soo
Song Young-Goo
Choi Hee-Jung
Peck Kyong-Ran
Kang Cheol-In
Kim Hyo-Youl
Kim Young-Keun
Lee Seung-Soon
Park Dae-Won
Kim Yeon-A
Choi Suk Hoon
Kim June-Myung
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Abstract
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Background: Surgical site infection (SSI) is prominent among the total incidence of healthcare-associated infections, and is a major contributing factor in the trend of increasing medical costs. There have been numerous efforts to analyze the conditions and causes of SSI for the purpose of prevention. In this study of SSI development after gastric surgery, we evaluated the prevalence of specific pathogens and compared the clinical characteristics observed between gram-positive (GPB) and gram-negative bacteria (GNB).
Materials and Methods: We conducted a retrospective study of patients who developed SSI within 30 days after gastric surgery at 13 clinics in Korea, between January 2007 and December 2008. Only those cases of SSI which included confirmed pathogen were included in this study.
Results: Among the 121 patients who developed SSI, GPB were observed in 32 patients and 36 cases, and GNB were isolated in 32 patients and 36 cases. Methicillin resistant Staphylococcus aureus (MRSA) was the most frequently isolated pathogen in this analysis. There were no differences observed between the GPB and GNB group in terms of baseline characteristics, patient or procedure related risk factors, or factors associated with prophylactic antibiotics.
Conclusions: In the previous studies of the occurrence of SSI after gastric surgery, it was reported that the majority of observed pathogens were enteric GNB. Further studies of the incidence of SSI after gastric surgery, particularly those related to MRSA infection, are necessary.
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KEYWORD
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Surgical site infection, Gastric surgery, Pathogens, Gram-positive bacteria, Gram-negative bacteria
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